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trufit cb plug  (Smith & Nephew)

 
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    Structured Review

    Smith & Nephew trufit cb plug
    Trufit Cb Plug, supplied by Smith & Nephew, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plug/cb+plug+trufit/pmc12930055-15-0-3
    Average 86 stars, based on 1 article reviews
    trufit cb plug - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    other:

    Article Title: Current understanding of articular cartilage lesions in femoroacetabular impingement syndrome.
    Article Snippet: TruFit Plug (Smith & Nephew, San Antonio, TX, USA) is a synthetic resorbable acellular biphasic scaffold composed of polylactide-coglycolide copolymer (PLGA), calcium sulfate, polyglycolide fibers, and surfactant [192, 193].

    Article Title: Outcomes of cartilage repair techniques for chondral injury in the hip-a systematic review.
    Article Snippet: The systematic review found two articles that used an artificial plug, and both of them utilise the TruFit cartilage/bone (CB) plug (Smith & Nephew).

    Article Title: Current understanding of articular cartilage lesions in femoroacetabular impingement syndrome
    Article Snippet: TruFit Plug (Smith & Nephew, San Antonio, TX, USA) is a synthetic resorbable acellular biphasic scaffold composed of polylactide-coglycolide copolymer (PLGA), calcium sulfate, polyglycolide fibers, and surfactant [ , ].

    Article Title: Gradient scaffolds for osteochondral tissue engineering and regeneration.
    Article Snippet: For instance, the TruFit plug from Smith & Nephew is a Page 40 of 53Journal of Materials Chemistry B Jo ur na lo fM at er ia ls C he m is tr y B A cc ep te d M an us cr ip t Pu bl is he d on 1 6 Ju ly 2 02 0.

    Article Title: Enthesis repair - State of play.
    Article Snippet: The fibrocartilaginous enthesis is a highly specialised tissue interface that ensures a smooth mechanical transfer between tendon or ligament and bone through a fibrocartilage area.. This tissue is prone to injury and often does not heal, even after surgical intervention.. Enthesis augmentation approaches are challenging due to the complexity of the tissue that is characterised by the coexistence of a range of cellular and extracellular components, architectural features and mechanical properties within only hundreds of micrometres.

    Transmission Assay:

    Article Title: Emerging therapies for cartilage regeneration in currently excluded ‘red knee’ populations
    Article Snippet: .. However, issues with graft survivability, disease transmission, and integration have motivated tissue engineers to develop newer composite scaffolds that guide localized regeneration of the cartilage and bone layers of an osteochondral unit., Clinically, the TruFit Plug (Smith & Nephew, San Antonio TX) is one of the only synthetic osteochondral scaffolds that has been evaluated in patients, , with a subchondral phase containing calcium sulfate for bone regeneration and an articulating phase that relied on marrow stimulation for cartilage regeneration. ..

    Construct:

    Article Title: The Role of Cartilage Tissue Engineering in Osteoarthritis Treatment: The Bench to Bedside Translation
    Article Snippet: .. TruFit Plug (Smith and Nephew) is probably the only synthetic osteochondral construct (only for focal defects) evaluated in human patients [87], Here, the subchondral bony component contains calcium sulfate for bone regeneration and a soft phase for cartilage regeneration. ..

    Polymer:

    Article Title: Biophysical signal-driven scaffold design for stem cell-guided osteochondral regeneration
    Article Snippet: ChondroMimeticTM (TiGenix/Col Solutions) , Biphasic collagen scaffold with a cartilage phase of collagen and GAGs and a bone phase containing Col plus CaP , Compositional and porosity contrast between cartilage-like and bone-like regions, a single integrated porous body , A Single-arm clinical study in 17 knees shows approximately 95% defect fill, repair tissue T2 values comparable to native cartilage, and improved KOOS and modified Cincinnati scores at a mean follow-up of 7.9 years. , [ , , ] . .. TruFit® CB plug (Smith & Nephew) , Cylindrical resorbable scaffold of PLGA with CaSO 4 and hydroxyapatite, with distinct chondral and osseous regions , Porous polymer−ceramic composite, early mechanical support with gradual load transfer during resorption , Multiple case series and systematic reviews show short-term symptom relief but frequent incomplete osseous integration and subchondral cysts, leading to variable outcomes and eventual withdrawal from routine clinical use. , [ , , ] . .. Biphasic PLGA/β-TCP osteochondral composite with minced autologous cartilage (Chiang/Tseng/Kuo) , Cylindrical biphasic DL-PLGA scaffold with a lower phase impregnated with β-TCP for bone and an upper chamber filled intraoperatively with double-minced autologous cartilage , Stiffness and composition contrast between the bone-phase polymer−ceramic and cartilage-filled phase, porous architecture for bone regeneration , A pilot study of 10 knees shows improvements in KOOS scores and hyaline-like cartilage regeneration with cancellous bone reconstruction at two years. A 5-year follow-up study and a recent randomized trial report durable clinical benefit and better KOOS outcomes than microfracture. , [ , , ] .



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    (A) Final deployment of the physician-modified candy plug (CP) ( red arrows indicate the proximal and distal struts of the modified stent graft). An 18-mm <t>Amplatzer</t> Vascular Plug II is positioned within its constrained central lumen ( blue arrows indicate the proximal and distal nitinol mesh lobes). (B) Complete thrombosis of the false lumen (FL) with cessation of retrograde flow above the CP devices. The vascular plug within the physician-modified CP is indicated by the blue arrow . (C) Volume-rendering technique reconstruction demonstrating the thoracic endovascular repair (TEVAR) and CP devices.
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    Image Search Results


    Under intravascular ultrasound (IVUS) guidance, the dissection flap was punctured from the true lumen into the false lumen (FL) approximately 2 cm distal to the caudal end of the thoracic stent graft, and a Radifocus guidewire was advanced into the FL (A) . The fenestration was then dilated using an 8 mm × 4 cm balloon catheter (B) . The modified Excluder aortic extender (Ex-cuff) was deployed at the distal level of the thoracic stent graft (C) . Subsequently, a 16-mm Amplatzer Vascular Plug I, preloaded with a 2.2F microcatheter was deployed at the waist of the modified Ex-cuff (D) . The microcatheter was then withdrawn into the plug, and four detachable coils were placed within the plug (E and F) . Angiography revealed persistent perigraft leakage around the Ex-cuff (G) . Therefore, 33% n-butyl-2-cyanoacrylate (NBCA) was slowly injected, achieving complete occlusion (H) ( arrowhead , coil-in-plug; arrow , NBCA-Lipiodol). Completion angiography confirmed complete elimination of FL perfusion in the thoracic aortic segment (I) .

    Journal: Journal of Vascular Surgery Cases, Innovations and Techniques

    Article Title: Black candy-plug technique for a large false lumen in a patient with complicated type B aortic dissection

    doi: 10.1016/j.jvscit.2026.102212

    Figure Lengend Snippet: Under intravascular ultrasound (IVUS) guidance, the dissection flap was punctured from the true lumen into the false lumen (FL) approximately 2 cm distal to the caudal end of the thoracic stent graft, and a Radifocus guidewire was advanced into the FL (A) . The fenestration was then dilated using an 8 mm × 4 cm balloon catheter (B) . The modified Excluder aortic extender (Ex-cuff) was deployed at the distal level of the thoracic stent graft (C) . Subsequently, a 16-mm Amplatzer Vascular Plug I, preloaded with a 2.2F microcatheter was deployed at the waist of the modified Ex-cuff (D) . The microcatheter was then withdrawn into the plug, and four detachable coils were placed within the plug (E and F) . Angiography revealed persistent perigraft leakage around the Ex-cuff (G) . Therefore, 33% n-butyl-2-cyanoacrylate (NBCA) was slowly injected, achieving complete occlusion (H) ( arrowhead , coil-in-plug; arrow , NBCA-Lipiodol). Completion angiography confirmed complete elimination of FL perfusion in the thoracic aortic segment (I) .

    Article Snippet: Subsequently, a 16-mm Amplatzer Vascular Plug I (Abbott), preloaded with a 2.2F-microcatheter (Coiling Support, HI-LEX Co) was delivered through a 6F guiding catheter (Destination; Terumo Medical Co) and deployed at the waist of the modified Ex-cuff ( , D ).

    Techniques: Dissection, Modification, Injection

    (A) Final deployment of the physician-modified candy plug (CP) ( red arrows indicate the proximal and distal struts of the modified stent graft). An 18-mm Amplatzer Vascular Plug II is positioned within its constrained central lumen ( blue arrows indicate the proximal and distal nitinol mesh lobes). (B) Complete thrombosis of the false lumen (FL) with cessation of retrograde flow above the CP devices. The vascular plug within the physician-modified CP is indicated by the blue arrow . (C) Volume-rendering technique reconstruction demonstrating the thoracic endovascular repair (TEVAR) and CP devices.

    Journal: Journal of Vascular Surgery Cases, Innovations and Techniques

    Article Title: Use of a physician-modified candy plug to rescue gutter leak arising from a collapsed candy plug

    doi: 10.1016/j.jvscit.2026.102175

    Figure Lengend Snippet: (A) Final deployment of the physician-modified candy plug (CP) ( red arrows indicate the proximal and distal struts of the modified stent graft). An 18-mm Amplatzer Vascular Plug II is positioned within its constrained central lumen ( blue arrows indicate the proximal and distal nitinol mesh lobes). (B) Complete thrombosis of the false lumen (FL) with cessation of retrograde flow above the CP devices. The vascular plug within the physician-modified CP is indicated by the blue arrow . (C) Volume-rendering technique reconstruction demonstrating the thoracic endovascular repair (TEVAR) and CP devices.

    Article Snippet: The constrained central lumen of the physician-modified CP was plugged with an 18-mm Amplatzer Vascular Plug II (Abbott Vascular) ( , A ).

    Techniques: Modification